Yes. Both a power supply and an LED driver are needed. A power supply provides power to the driver, while the driver controls the current to the LED Module.
The voltage rating of the power supply needs to be a few volts higher than the total Forward Voltage (Vf) of all the series-connected LEDs you are powering. You will find more details in this article.
The current rating of the power supply must be equal to or higher than the maximum current rating of the driver you are using.